5T3U

Crystal Structure of the PTS IIA protein associated with the fucose utilization operon from Streptococcus pneumoniae

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5t3ua1	Alpha and beta proteins (a/b)	PTS system fructose IIA component-like	PTS system fructose IIA component-like	automated matches	automated matches	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
A	d5t3ua2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
B	d5t3ub1	Alpha and beta proteins (a/b)	PTS system fructose IIA component-like	PTS system fructose IIA component-like	automated matches	automated matches	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)
B	d5t3ub2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Streptococcus pneumoniae TIGR4 ) [TaxId: 170187 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	PTS system fructose IIA component-like	8083015	3000475	SCOP2B (2022-06-29)
B	SCOP2 Family	EIIA-man component-like	8083014	4000512	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	PTS system fructose IIA component-like	8083015	3000475	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03610	e5t3uA1	A: a/b three-layered sandwiches	X: EDD domain (From Topology)	H: EDD domain (From Topology)	T: EDD domain	F: PF03610	ECOD (1.6)
B	PF03610	e5t3uB1	A: a/b three-layered sandwiches	X: EDD domain (From Topology)	H: EDD domain (From Topology)	T: EDD domain	F: PF03610	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.510	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Phosphotransferase system, mannose-type IIA component	CATH (4.3.0)
B	3.40.50.510	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Phosphotransferase system, mannose-type IIA component	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03610	PTS system fructose IIA component (EIIA-man)	PTS system fructose IIA component	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	PTS system, IIA component	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups	phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization phosphorylation cellular metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport organic substance transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization carbohydrate transmembrane transport	membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036662	Phosphotransferase system, mannose-type IIA component superfamily	Homologous Superfamily
A, B	IPR004701	Phosphotransferase system, mannose-type IIA component	Domain
A, B	IPR033887	PTS system mannose/sorbose specific IIA subunit	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.