5JSN
Bcl2-inhibitor complex
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C | PF00452,PF02180 | e5jsnC1 | A: alpha arrays | X: Toxins' membrane translocation domains | H: Bcl-2 inhibitors of programmed cell death (From Topology) | T: Bcl-2 inhibitors of programmed cell death | F: PF00452,PF02180 | ECOD (1.6) |
A | PF00452,PF02180 | e5jsnA1 | A: alpha arrays | X: Toxins' membrane translocation domains | H: Bcl-2 inhibitors of programmed cell death (From Topology) | T: Bcl-2 inhibitors of programmed cell death | F: PF00452,PF02180 | ECOD (1.6) |
D | F_UNCLASSIFIED | e5jsnD1 | A: a+b two layers | X: RRF/tRNA synthetase additional domain-like | H: Ribosome recycling factor, RRF (From Topology) | T: Ribosome recycling factor, RRF | F: F_UNCLASSIFIED | ECOD (1.6) |
B | F_UNCLASSIFIED | e5jsnB1 | A: a+b two layers | X: RRF/tRNA synthetase additional domain-like | H: Ribosome recycling factor, RRF (From Topology) | T: Ribosome recycling factor, RRF | F: F_UNCLASSIFIED | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
D | 1.10.132.20 | Mainly Alpha | Orthogonal Bundle | Topoisomerase I | Chain A, domain 4 | CATH (4.3.0) |
B | 1.10.132.20 | Mainly Alpha | Orthogonal Bundle | Topoisomerase I | Chain A, domain 4 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02180 | Bcl-2 homology region 4 (BH4) | Bcl-2 homology region 4 | - | Family | |
PF00452 | Apoptosis regulator proteins, Bcl-2 family (Bcl-2) | Apoptosis regulator proteins, Bcl-2 family | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036834 | Bcl-2-like superfamily | Homologous Superfamily | |
IPR020731 | Apoptosis regulator, Bcl-2, BH4 motif, conserved site | Conserved Site | |
IPR046371 | Bcl-2, Bcl-2 homology region 1-3 | Domain | |
IPR020717 | Apoptosis regulator, Bcl-2, BH1 motif, conserved site | Conserved Site | |
IPR004725 | Apoptosis regulator, Bcl-2/ BclX | Family | |
IPR003093 | Apoptosis regulator, Bcl-2 protein, BH4 | Domain | |
IPR002475 | Bcl2-like | Family | |
IPR020728 | Apoptosis regulator, Bcl-2, BH3 motif, conserved site | Conserved Site | |
IPR020726 | Apoptosis regulator, Bcl-2, BH2 motif, conserved site | Conserved Site | |
IPR013278 | Apoptosis regulator, Bcl-2 | Family | |
IPR026298 | Bcl-2 family | Family |