5FT1

Crystal structure of gp37(Dip) from bacteriophage phiKZ bound to RNase E of Pseudomonas aeruginosa

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF17679	e5ft1A1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)
B	PF17679	e5ft1B1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)
E	PF17679	e5ft1E1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)
G	PF17679	e5ft1G1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)
I	PF17679	e5ft1I1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)
K	PF17679	e5ft1K1	A: a+b two layers	X: RNase inhibitor Dip (From Topology)	H: RNase inhibitor Dip (From Topology)	T: RNase inhibitor Dip	F: PF17679	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, E, G, I A, B, E, G, I, K	PF17679	gp37/Dip protein (Dip)	gp37/Dip protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, E, G, I A, B, E, G, I, K	GP37	-	-	-
C, D, F, H, J C, D, F, H, J, L	RIBONUCLEASE E	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding ribonuclease E activity nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding ribonuclease E activity nuclease activity hydrolase activity, acting on ester bonds catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity RNA binding organic cyclic compound binding rRNA binding nucleic acid binding endonuclease activity RNA endonuclease activity transition metal ion binding zinc ion binding tRNA binding	regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of cellular process catabolic process cellular biosynthetic process negative regulation of biological process RNA metabolic process negative regulation of cellular metabolic process macromolecule catabolic process nucleobase-containing compound metabolic process organic substance metabolic process organic substance biosynthetic process negative regulation of cellular process RNA catabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process mRNA catabolic process regulation of biological process cellular metabolic process negative regulation of metabolic process biological regulation regulation of cellular metabolic process primary metabolic process regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process mRNA metabolic process negative regulation of cellular biosynthetic process nucleic acid metabolic process organic cyclic compound catabolic process nucleobase-containing compound catabolic process regulation of cellular biosynthetic process regulation of gene expression organic cyclic compound metabolic process negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process nucleic acid catabolic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process organic substance catabolic process ribonucleoprotein complex biogenesis rRNA processing cellular component biogenesis ribosome biogenesis cellular component organization or biogenesis RNA processing rRNA metabolic process tRNA metabolic process tRNA processing	intracellular anatomical structure cytoplasm cellular anatomical entity cell periphery cytoplasmic side of plasma membrane cytoplasmic side of membrane membrane plasma membrane side of membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, E, G, I A, B, E, G, I, K	IPR040860	Gp37/Dip protein	Family
C, D, F, H, J C, D, F, H, J, L	IPR028878	Ribonuclease E	Family
C, D, F, H, J C, D, F, H, J, L	IPR003029	S1 domain	Domain
C, D, F, H, J C, D, F, H, J, L	IPR019307	RNA-binding protein AU-1/Ribonuclease E/G	Family
C, D, F, H, J C, D, F, H, J, L	IPR004659	Ribonuclease E/G	Family
C, D, F, H, J C, D, F, H, J, L	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
C, D, F, H, J C, D, F, H, J, L	IPR048583	RNase E/G, thioredoxin-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.