5DOR

P2 Integrase catalytic domain in space group P21

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5dora_	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Integrase (Int)	(Peduovirus P2 ) [TaxId: 10679 ],	SCOPe (2.08)
B	d5dorb_	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Integrase (Int)	(Peduovirus P2 ) [TaxId: 10679 ],	SCOPe (2.08)
C	d5dorc_	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Integrase (Int)	(Peduovirus P2 ) [TaxId: 10679 ],	SCOPe (2.08)
D	d5dord_	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Integrase (Int)	(Peduovirus P2 ) [TaxId: 10679 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8078465	3001127	SCOP2B (2022-06-29)
B	SCOP2 Family	Lambda integrase-like catalytic core	8078464	4002347	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	DNA breaking-rejoining enzymes	8078465	3001127	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8078465	3001127	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8078465	3001127	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Phage_integrase_C	e5dorA1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_C	ECOD (1.6)
A	Phage_integrase_N_1	e5dorA2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N_1	ECOD (1.6)
B	Phage_integrase_C	e5dorB2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_C	ECOD (1.6)
B	Phage_integrase_N_1	e5dorB1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N_1	ECOD (1.6)
C	Phage_integrase_C	e5dorC1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_C	ECOD (1.6)
C	Phage_integrase_N_1	e5dorC2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N_1	ECOD (1.6)
D	Phage_integrase_C	e5dorD1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_C	ECOD (1.6)
D	Phage_integrase_N_1	e5dorD2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
B	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
C	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
D	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00589	Phage integrase family (Phage_integrase)	Phage integrase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Integrase	DNA binding binding organic cyclic compound binding nucleic acid binding hydrolase activity catalytic activity transferase activity	establishment of integrated proviral latency viral latency viral process establishment of viral latency biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process establishment of integrated proviral latency viral latency viral process establishment of viral latency biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process DNA integration nucleic acid metabolic process viral genome integration into host DNA DNA recombination	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR011010	DNA breaking-rejoining enzyme, catalytic core	Homologous Superfamily
A, B, C, D	IPR044068	Core-binding (CB) domain	Domain
A, B, C, D	IPR002104	Integrase, catalytic domain	Domain
A, B, C, D	IPR013762	Integrase-like, catalytic domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.