5DHX

HIV-1 Rev NTD dimers with variable crossing angles

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
IMGT Antibody Annotation
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth B]	d5dhxb1	All beta proteins	Immunoglobulin-like beta-sandwich	Immunoglobulin	automated matches	automated matches	Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ], Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
A [auth B]	d5dhxb2	Artifacts	Tags	Tags	Tags	C-terminal Tags	Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ], Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
C [auth L]	d5dhxl1	All beta proteins	Immunoglobulin-like beta-sandwich	Immunoglobulin	automated matches	automated matches	Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ], Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)
C [auth L]	d5dhxl3	Artifacts	Tags	Tags	Tags	C-terminal Tags	Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ], Rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	V-set_8	e5dhxB2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
A [auth B]	V-set	e5dhxB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
C [auth L]	V-set_8	e5dhxL2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
C [auth L]	V-set	e5dhxL1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
B [auth C]	REV	e5dhxC1	A: alpha bundles	X: HIV Rev (From Topology)	H: HIV Rev (From Topology)	T: HIV Rev	F: REV	ECOD (1.6)
D [auth M]	REV	e5dhxM1	A: alpha bundles	X: HIV Rev (From Topology)	H: HIV Rev (From Topology)	T: HIV Rev	F: REV	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth B]	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
C [auth L]	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)
B [auth C]	6.10.140.630	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)
D [auth M]	6.10.140.630	Special	Helix non-globular	Helix Hairpins		CATH (4.3.0)

IMGT Antibody Annotation IMGT Database Homepage

Chain	Protein Name	Description	Organism Name	Gene Allele Name(s)	Domain Name(s)	Receptor Type	Receptor Description	Provenance Source
A [auth B], C [auth L]	Fab, anti-Rev	V-KAPPA	Oryctolagus cuniculus (rabbit)	IGKV1S302, IGKJ1-204	V-DOMAIN V-KAPPA	IG	FV-HEAVY_KAPPA	IMGT (202415-0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth C], D [auth M]	PF00424	REV protein (anti-repression trans-activator protein) (REV)	REV protein (anti-repression trans-activator protein)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], C [auth L]	Anti-Rev Antibody Fab single-chain variable fragment, light chain,Anti-Rev Antibody Fab single-chain variable fragment, heavy chain	-	-	-
B [auth C], D [auth M]	Protein Rev	transcription regulator activity DNA-binding transcription factor activity RNA binding binding organic cyclic compound binding nucleic acid binding	RNA transport nitrogen compound transport transport organic substance transport nucleic acid transport mRNA transport establishment of localization localization establishment of RNA localization macromolecule localization RNA localization nucleobase-containing compound transport protein localization cellular localization RNA transport nitrogen compound transport transport organic substance transport nucleic acid transport mRNA transport establishment of localization localization establishment of RNA localization macromolecule localization RNA localization nucleobase-containing compound transport protein localization cellular localization establishment of protein localization nucleocytoplasmic transport nuclear transport intracellular transport protein export from nucleus protein transport establishment of localization in cell cellular macromolecule localization cellular process nuclear export intracellular protein transport viral process	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell part host intracellular region cellular anatomical entity host cell nucleus host cell nucleolus host cell nuclear part host intracellular organelle host cell cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth C], D [auth M]	IPR000625	Anti-repression trans-activator protein, REV protein	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.