5C2U
Ferredoxin-like domain of nucleoporin Nup54 bound to a nanobody
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth B] | d5c2ub_ | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | (Camelus dromedarius ) [TaxId: 9838 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B [auth A] | SCOP2 Family | Nup54-like | 8049318 | 4006450 | SCOP2 (2022-06-29) |
B [auth A] | SCOP2 Superfamily | Nup54 ferredoxin-like domain-like | 8053274 | 3002172 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A [auth B] | PF07686 | e5c2uB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
B [auth A] | F_UNCLASSIFIED | e5c2uA1 | A: a+b two layers | X: Alpha-beta plaits | H: Nup54 ferredoxin-like domain (From Topology) | T: Nup54 ferredoxin-like domain | F: F_UNCLASSIFIED | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A [auth B] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
A [auth B] | Arabian camel heavy chain VH domain | VH | Camelus dromedarius (Arabian camel) | IGHV3S1*01, IGHJ4*01 | V-DOMAIN VH | IG | (VH) | IMGT (202421-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
A [auth B] | Heavy Chain | IGHV1 | - | nup54 | SAbDab (2024-05-31) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
B [auth A] | PF13874 | Nucleoporin complex subunit 54 (Nup54) | Nucleoporin complex subunit 54 | This is the human Nup54 subunit of the nucleoporin complex, equivalent to Nup57 of yeast. Nup54, Nup58 and Nup62 all have similar affinities for importin-beta. It seems likely that they are the only FG-repeat nucleoporins of the central channel, and ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
B [auth A] | IPR025712 | Nucleoporin Nup54, alpha-helical domain | Domain |
B [auth A] | IPR040985 | Nup54, C-terminal interacting domain | Domain |
B [auth A] | IPR024864 | Nucleoporin Nup54/Nup57/Nup44 | Family |