4P79

Crystal structure of mouse claudin-15

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d4p79a1	Membrane and cell surface proteins and peptides	Claudin-like	Claudin-like	Claudin	Claudin-15	Mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)
A	d4p79a2	Artifacts	Tags	Tags	Tags	N-terminal Tags	Mouse (Mus musculus ) [TaxId: 10090 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Claudin-like	8048284	4006038	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Claudin-like	8092549	3002606	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PMP22_Claudin	e4p79A1	A: alpha bundles	X: Bromodomain-like	H: Claudin (From Topology)	T: Claudin	F: PMP22_Claudin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.140.150	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00822	PMP-22/EMP/MP20/Claudin family (PMP22_Claudin)	PMP-22/EMP/MP20/Claudin family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Claudin-15	structural molecule activity identical protein binding protein binding binding	bicellular tight junction assembly tight junction organization apical junction assembly cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly tight junction assembly cellular process cellular component organization or biogenesis cell-cell junction assembly cell-cell junction organization cell adhesion bicellular tight junction assembly tight junction organization apical junction assembly cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly tight junction assembly cellular process cellular component organization or biogenesis cell-cell junction assembly cell-cell junction organization cell adhesion cell-cell adhesion calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules cell-cell adhesion via plasma-membrane adhesion molecules localization transport monoatomic ion transport establishment of localization	cell-cell junction apical junction complex bicellular tight junction tight junction anchoring junction cell junction cellular anatomical entity cell periphery plasma membrane membrane lateral plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR006187	Claudin	Family
A	IPR017974	Claudin, conserved site	Conserved Site
A	IPR008094	Claudin-15	Family
A	IPR004031	PMP-22/EMP/MP20/Claudin	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Transmembrane	Alpha-helical polytopic	Tetraspan junctional complexes	Claudin

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Claudins	Caludin-15

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.