4MT4

Crystal structure of the Campylobacter jejuni CmeC outer membrane channel

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF02321	e4mt4A1	A: a+b duplicates or obligate multimers	X: Outer membrane efflux proteins (OEP) (From Topology)	H: Outer membrane efflux proteins (OEP) (From Topology)	T: Outer membrane efflux proteins (OEP)	F: PF02321	ECOD (1.6)
B	PF02321	e4mt4B1	A: a+b duplicates or obligate multimers	X: Outer membrane efflux proteins (OEP) (From Topology)	H: Outer membrane efflux proteins (OEP) (From Topology)	T: Outer membrane efflux proteins (OEP)	F: PF02321	ECOD (1.6)
C	PF02321	e4mt4C1	A: a+b duplicates or obligate multimers	X: Outer membrane efflux proteins (OEP) (From Topology)	H: Outer membrane efflux proteins (OEP) (From Topology)	T: Outer membrane efflux proteins (OEP)	F: PF02321	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.1600.10	Mainly Alpha	Up-down Bundle	Outer membrane efflux proteins (OEP)	Outer membrane efflux proteins (OEP)	CATH (4.3.0)
B	1.20.1600.10	Mainly Alpha	Up-down Bundle	Outer membrane efflux proteins (OEP)	Outer membrane efflux proteins (OEP)	CATH (4.3.0)
C	1.20.1600.10	Mainly Alpha	Up-down Bundle	Outer membrane efflux proteins (OEP)	Outer membrane efflux proteins (OEP)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF02321	Outer membrane efflux protein (OEP)	Outer membrane efflux protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	CmeC	efflux transmembrane transporter activity transporter activity transmembrane transporter activity	-	cell periphery plasma membrane membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR003423	Outer membrane efflux protein	Family
A, B, C	IPR010131	RND efflux system, outer membrane lipoprotein, NodT	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C	OPM	Transmembrane	Beta-barrel transmembrane	Outer membrane efflux proteins (n=12,S=18) trimeric	Outer membrane efflux proteins

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C	mpstruc	TRANSMEMBRANE PROTEINS: BETA-BARREL	Beta-Barrel Membrane Proteins: Monomeric/Dimeric	CmeC bacterial multi-drug efflux transporter outer membrane channel

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.