4LVN
Crystal structure of PfSUB1-prodomain-NIMP.M7 Fab complex
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d4lvnb2 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | C1 set domains (antibody constant domain-like) | automated matches | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
B | d4lvnb1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | automated matches | automated matches | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
C | d4lvnc1 | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | V set domains (antibody variable domain-like) | automated matches | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
C | d4lvnc2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | (Mus musculus ) [TaxId: 10090 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | PF00082 | e4lvnA1 | A: a/b three-layered sandwiches | X: Subtilisin-like | H: Subtilisin-like (From Topology) | T: Subtilisin-like | F: PF00082 | ECOD (1.6) |
B | PF07654 | e4lvnB1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07654 | ECOD (1.6) |
B | PF07686 | e4lvnB2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
C | PF07654 | e4lvnC1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07654 | ECOD (1.6) |
C | PF07686 | e4lvnC2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: PF07686 | ECOD (1.6) |
D [auth P] | PF18213 | e4lvnP1 | A: a+b two layers | X: Alpha-beta plaits | H: Protease propeptides/inhibitors (From Topology) | T: Protease propeptides/inhibitors | F: PF18213 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.50.200 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Peptidase S8/S53 domain | CATH (4.3.0) |
B | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
C | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
D [auth P] | 3.30.70.2380 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
NIMP.M7 FAB HEAVY CHAIN | L-KAPPA | Mus musculus (house mouse) | IGKV4-74*01, IGKJ5*01, IGKC*01, IGKC*02 | V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA | IG | FAB-GAMMA-1_KAPPA | IMGT (202418-0) | |
NIMP.M7 FAB HEAVY CHAIN | VH-CH1 | Mus musculus (house mouse) | IGHV3-1*02, IGHJ1*01, IGHJ1*02, IGHG1*01, IGHG1*02 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-1_KAPPA | IMGT (202418-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
Light Chain | IGKV4 | Kappa | subtilisin-like serine protease | SAbDab (2024-05-10) | |
Heavy Chain | IGHV3 | - | subtilisin-like serine protease | SAbDab (2024-05-10) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00082 | Subtilase family (Peptidase_S8) | Subtilase family | Subtilases are a family of serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like that found in the trypsin serine proteases (see Pfam:PF00089). Structure is an alpha/beta fold containing a 7 ... | Domain | |
D [auth P] | PF18213 | SUB1 protease Prodomain ProdP9 (SUB1_ProdP9) | SUB1 protease Prodomain ProdP9 | This domain is the bound prodomain fragment ProdP9 of the SUB1 protein present in Plasmodium falciparum. SUB1 is a serine protease that processes a subset of parasite proteins that play indispensable roles in egress and invasion. The C-terminal stal ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
Subtilisin-like serine protease | ||||
NIMP.M7 Fab light chain | - | - | - | |
NIMP.M7 Fab heavy chain | - | - | - | |
D [auth P] | Subtilisin-like serine protease |