Annotations: 4LQK

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth C]	SCOP2 Family	VACV protein N1-like	8047915	4005875	SCOP2 (2022-06-29)
A [auth C]	SCOP2 Superfamily	Bcl-2-like inhibitors of programmed cell death	8052542	3001974	SCOP2 (2022-06-29)
B [auth D]	SCOP2B Superfamily	Bcl-2-like inhibitors of programmed cell death	8052542	3001974	SCOP2B (2022-06-29)
C [auth A]	SCOP2B Superfamily	Bcl-2-like inhibitors of programmed cell death	8052542	3001974	SCOP2B (2022-06-29)
D [auth B]	SCOP2B Superfamily	Bcl-2-like inhibitors of programmed cell death	8052542	3001974	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth C]	PF06227	e4lqkC1	A: alpha arrays	X: Toxins' membrane translocation domains	H: Bcl-2 inhibitors of programmed cell death (From Topology)	T: Bcl-2 inhibitors of programmed cell death	F: PF06227	ECOD (1.6)
B [auth D]	PF06227	e4lqkD1	A: alpha arrays	X: Toxins' membrane translocation domains	H: Bcl-2 inhibitors of programmed cell death (From Topology)	T: Bcl-2 inhibitors of programmed cell death	F: PF06227	ECOD (1.6)
C [auth A]	PF06227	e4lqkA1	A: alpha arrays	X: Toxins' membrane translocation domains	H: Bcl-2 inhibitors of programmed cell death (From Topology)	T: Bcl-2 inhibitors of programmed cell death	F: PF06227	ECOD (1.6)
D [auth B]	PF06227	e4lqkB1	A: alpha arrays	X: Toxins' membrane translocation domains	H: Bcl-2 inhibitors of programmed cell death (From Topology)	T: Bcl-2 inhibitors of programmed cell death	F: PF06227	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth C]	1.10.437.20	Mainly Alpha	Orthogonal Bundle	Apoptosis Regulator Bcl-x	dsDNA poxvirus	CATH (4.3.0)
B [auth D]	1.10.437.20	Mainly Alpha	Orthogonal Bundle	Apoptosis Regulator Bcl-x	dsDNA poxvirus	CATH (4.3.0)
C [auth A]	1.10.437.20	Mainly Alpha	Orthogonal Bundle	Apoptosis Regulator Bcl-x	dsDNA poxvirus	CATH (4.3.0)
D [auth B]	1.10.437.20	Mainly Alpha	Orthogonal Bundle	Apoptosis Regulator Bcl-x	dsDNA poxvirus	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth C], B [auth D], C [auth A], D [auth B]	PF06227	Poxvirus Bcl-2-like proteins (Poxv_Bcl-2-like)	Poxvirus Bcl-2-like proteins	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth D], C [auth A], D [auth B]	Protein A46	molecular sequestering activity protein sequestering activity	symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms response to stimulus response to biotic stimulus biological process involved in symbiotic interaction symbiont-mediated suppression of host immune response symbiont-mediated suppression of host innate immune response response to host immune response symbiont-mediated suppression of host defenses symbiont-mediated perturbation of host innate immune response response to host response to external biotic stimulus symbiont-mediated perturbation of host signal transduction pathway modulation of process of another organism symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms response to stimulus response to biotic stimulus biological process involved in symbiotic interaction symbiont-mediated suppression of host immune response symbiont-mediated suppression of host innate immune response response to host immune response symbiont-mediated suppression of host defenses symbiont-mediated perturbation of host innate immune response response to host response to external biotic stimulus symbiont-mediated perturbation of host signal transduction pathway modulation of process of another organism symbiont-mediated perturbation of host defense response response to host defenses response to other organism symbiont-mediated perturbation of host immune response response to defenses of other organism symbiont-mediated perturbation of host defenses response to external stimulus biological process involved in interaction with host symbiont-mediated suppression of host signal transduction pathway modulation by symbiont of host process symbiont-mediated suppression of host toll-like receptor signaling pathway cellular process symbiont-mediated suppression of host pathogen-associated molecular pattern receptor signaling pathway symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity symbiont-mediated suppression of cytoplasmic pattern recognition receptor signaling pathway	cell periphery extrinsic component of plasma membrane cytoplasmic side of plasma membrane cytoplasmic side of membrane membrane plasma membrane cellular anatomical entity extrinsic component of membrane extrinsic component of cytoplasmic side of plasma membrane side of membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth C], B [auth D], C [auth A], D [auth B]	IPR022819	Poxvirus Bcl-2-like	Family
A [auth C], B [auth D], C [auth A], D [auth B]	IPR043018	Poxvirus domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.