Annotations: 4K90

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2 Family	FTP-like	8049614	4006558	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	FTP/YycH/YycI-like	8092135	3002371	SCOP2 (2022-06-29)
A	SCOP2 Family	Thermolysin-like	8049889	4001610	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Metalloproteases (zincins) catalytic domain	8092136	3001975	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	F_UNCLASSIFIED	e4k90B5	A: a+b two layers	X: Cystatin-like	H: Cystatin/monellin (From Topology)	T: Cystatin/monellin	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF07504	e4k90B6	A: a+b two layers	X: Cystatin-like	H: Cystatin/monellin (From Topology)	T: Cystatin/monellin	F: PF07504	ECOD (1.6)
A	PF02128	e4k90A1	A: mixed a+b and a/b	X: Zincin-like	H: Metalloproteases (zincins) catalytic domain (From Topology)	T: Metalloproteases (zincins) catalytic domain	F: PF02128	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.170.10	Alpha Beta	Roll	Elastase	domain 1	CATH (4.3.0)
A	1.10.390.10	Mainly Alpha	Orthogonal Bundle	Neutral Protease	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF07504	Fungalysin/Thermolysin Propeptide Motif (FTP)	Fungalysin/Thermolysin Propeptide Motif	-	Motif
A	PF02128	Fungalysin metallopeptidase (M36) (Peptidase_M36)	Fungalysin metallopeptidase (M36)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Extracellular metalloproteinase mep	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding peptidase activity catalytic activity, acting on a protein metalloendopeptidase activity hydrolase activity metallopeptidase activity catalytic activity endopeptidase activity	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process	extracellular region extracellular space cellular anatomical entity
A	Extracellular metalloproteinase mep	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding peptidase activity catalytic activity, acting on a protein metalloendopeptidase activity hydrolase activity metallopeptidase activity catalytic activity endopeptidase activity	organic substance metabolic process organonitrogen compound metabolic process proteolysis metabolic process primary metabolic process protein metabolic process macromolecule metabolic process	extracellular region extracellular space cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR001842	Peptidase M36, fungalysin	Family
B	IPR027268	Peptidase M4/M1, CTD superfamily	Homologous Superfamily
B	IPR011096	FTP domain	Domain
A	IPR001842	Peptidase M36, fungalysin	Family
A	IPR027268	Peptidase M4/M1, CTD superfamily	Homologous Superfamily
A	IPR011096	FTP domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.