4IGL

Structure of the RHS-repeat containing BC component of the secreted ABC toxin complex from Yersinia entomophaga

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	NTD-SpvB-like	8051661	4007457	SCOP2 (2022-06-29)
A	SCOP2 Family	TcB TcA-binding domain-like	8047403	4005626	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Effector protein SpvB N-terminal domain-like	8102233	3002724	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PAL-like	8102242	3002726	SCOP2 (2022-06-29)
C	SCOP2B Superfamily	PAL-like	8102242	3002726	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Effector protein SpvB N-terminal domain-like	8102233	3002724	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03534,PF12255,PF12256	e4iglA1	A: beta meanders	X: Rearrangement hotspot (RHS) repeats protein (From Topology)	H: Rearrangement hotspot (RHS) repeats protein (From Topology)	T: Rearrangement hotspot (RHS) repeats protein	F: PF03534,PF12255,PF12256	ECOD (1.6)
A	F_UNCLASSIFIED	e4iglA2	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: Propeller domain in ABC toxin B component	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF03534,PF12255,PF12256	e4iglC4	A: beta meanders	X: Rearrangement hotspot (RHS) repeats protein (From Topology)	H: Rearrangement hotspot (RHS) repeats protein (From Topology)	T: Rearrangement hotspot (RHS) repeats protein	F: PF03534,PF12255,PF12256	ECOD (1.6)
C	F_UNCLASSIFIED	e4iglC3	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: Propeller domain in ABC toxin B component	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF18807	e4iglB1	A: beta meanders	X: Rearrangement hotspot (RHS) repeats protein (From Topology)	H: Rearrangement hotspot (RHS) repeats protein (From Topology)	T: Rearrangement hotspot (RHS) repeats protein	F: PF18807	ECOD (1.6)
D	PF18807	e4iglD1	A: beta meanders	X: Rearrangement hotspot (RHS) repeats protein (From Topology)	H: Rearrangement hotspot (RHS) repeats protein (From Topology)	T: Rearrangement hotspot (RHS) repeats protein	F: PF18807	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.180.10.10	Mainly Beta	Shell	RHS repeat-associated core	RHS repeat-associated core	CATH (4.3.0)
D	2.180.10.10	Mainly Beta	Shell	RHS repeat-associated core	RHS repeat-associated core	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF12256	Insecticide toxin TcdB middle/N-terminal region (TcdB_toxin_midN)	Insecticide toxin TcdB middle/N-terminal region	-	Repeat
A, C	PF12255	Insecticide toxin TcdB middle/C-terminal region (TcdB_toxin_midC)	Insecticide toxin TcdB middle/C-terminal region	-	Family
A, C	PF03534	Salmonella virulence plasmid 65kDa B protein (SpvB)	Salmonella virulence plasmid 65kDa B protein	-	Family
B, D	PF18807	Tripartite Tc toxins repeat (TTc_toxin_rep)	Tripartite Tc toxins repeat	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	YenB	-	-	intracellular anatomical structure cytoplasm cellular anatomical entity extracellular region
B, D	YenC2	-	-	extracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR028994	Integrin alpha, N-terminal	Homologous Superfamily
A, C	IPR003284	Salmonella virulence plasmid 65kDa B protein	Family
A, C	IPR022044	Insecticide toxin TcdB middle/C-terminal	Domain
A, C	IPR022045	Insecticide toxin TcdB middle/N-terminal	Domain
B, D	IPR041508	Toxin complex C-like repeat	Repeat
B, D	IPR022385	Rhs repeat-associated core	Domain
B, D	IPR025968	YwqJ-like deaminase	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.