4E78
Crystal structure of a product state assembly of HCV NS5B genotype 2a JFH-1 isolate with beta hairpin loop deletion bound to primer-template RNA with 3'-dG
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C [auth A] | d4e78a1 | Multi-domain proteins (alpha and beta) | DNA/RNA polymerases | DNA/RNA polymerases | RNA-dependent RNA-polymerase | Viral RNA polymerase | HCV (Hepatitis C virus JFH-1 ) [TaxId: 356411 ], HCV (Hepatitis C virus JFH-1 ) [TaxId: 356411 ], | SCOPe (2.08) |
C [auth A] | d4e78a2 | Artifacts | Tags | Tags | Tags | N-terminal Tags | HCV (Hepatitis C virus JFH-1 ) [TaxId: 356411 ], HCV (Hepatitis C virus JFH-1 ) [TaxId: 356411 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
C [auth A] | PF00998 | e4e78A1 | A: alpha bundles | X: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | H: helical bundle domain in reverse transcriptase-like polymerases (From Topology) | T: helical bundle domain in reverse transcriptase-like polymerases | F: PF00998 | ECOD (1.6) |
C [auth A] | PF00998 | e4e78A2 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: PF00998 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
C [auth A] | PF00998 | Viral RNA dependent RNA polymerase (RdRP_3) | Viral RNA dependent RNA polymerase | - | Family |