Annotations: 3S6Y

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Fibre shaft of virus attachment proteins	8038300	3001872	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Virus attachment protein globular domain	8038299	3001376	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Fibre shaft of virus attachment proteins	8038300	3001872	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Virus attachment protein globular domain	8038299	3001376	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Virus attachment protein globular domain	8038299	3001376	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Fibre shaft of virus attachment proteins	8038300	3001872	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Reo_sigma1_C	e3s6yA1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Reo_sigma1_C	ECOD (1.6)
A	EUF07859,Reo_sigma1_N_1	e3s6yA3	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: EUF07859,Reo_sigma1_N_1	ECOD (1.6)
A	UNK_F_TYPE	e3s6yA2	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: UNK_F_TYPE	ECOD (1.6)
B	Reo_sigma1_C	e3s6yB1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Reo_sigma1_C	ECOD (1.6)
B	EUF07859,Reo_sigma1_N_1	e3s6yB3	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: EUF07859,Reo_sigma1_N_1	ECOD (1.6)
B	UNK_F_TYPE	e3s6yB2	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: UNK_F_TYPE	ECOD (1.6)
C	Reo_sigma1_C	e3s6yC1	A: beta sandwiches	X: Domain in virus attachment proteins (From Topology)	H: Domain in virus attachment proteins (From Topology)	T: Domain in virus attachment proteins	F: Reo_sigma1_C	ECOD (1.6)
C	EUF07859,Reo_sigma1_N_1	e3s6yC3	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: EUF07859,Reo_sigma1_N_1	ECOD (1.6)
C	UNK_F_TYPE	e3s6yC2	A: beta duplicates or obligate multimers	X: Triple beta-spiral (From Topology)	H: Triple beta-spiral (From Topology)	T: Triple beta-spiral	F: UNK_F_TYPE	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	6.20.10.20	Special	Other non-globular	Laminin		CATH (4.3.0)
C	6.10.250.3380	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)
C	2.10.25.20	Mainly Beta	Ribbon	Laminin	reovirus attachment protein sigma1	CATH (4.3.0)
C	2.60.90.20	Mainly Beta	Sandwich	Adenovirus Type 5 Fiber Protein (Receptor Binding Domain)	Virus attachment protein , globular domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF01664	Reovirus viral attachment protein sigma 1 (Reo_sigma1)	Reovirus viral attachment protein sigma 1	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	Outer capsid protein sigma-1	-	biological process involved in interspecies interaction between organisms symbiont entry into host cell viral process symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction virion attachment to host cell adhesion of symbiont to host cell adhesion of symbiont to host cell adhesion cellular process	viral capsid icosahedral viral capsid virion component viral outer capsid

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR009013	Attachment protein shaft domain superfamily	Homologous Superfamily
A, B, C	IPR008982	Adenovirus pIV-like, attachment domain	Homologous Superfamily
A, B, C	IPR002592	Viral attachment sigma 1, reoviral	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.