3QR7

Crystal structure of the C-terminal fragment of the bacteriophage P2 membrane-piercing protein gpV

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Phage fibre proteins	8095956	3000351	SCOP2B (2022-06-29)
B	SCOP2 Family	Membrane-piercing spike-like	8046357	4005039	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Phage fibre proteins	8095956	3000351	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Phage_Mu_Gp45	e3qr7A1	A: beta duplicates or obligate multimers	X: Phage tail fiber protein trimerization domain (From Topology)	H: Phage tail fiber protein trimerization domain (From Topology)	T: Phage tail fiber protein trimerization domain	F: Phage_Mu_Gp45	ECOD (1.6)
B	Phage_Mu_Gp45	e3qr7B1	A: beta duplicates or obligate multimers	X: Phage tail fiber protein trimerization domain (From Topology)	H: Phage tail fiber protein trimerization domain (From Topology)	T: Phage tail fiber protein trimerization domain	F: Phage_Mu_Gp45	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF18715	Phage spike trimer (Phage_spike)	Phage spike trimer	-	Repeat
A, B	PF18946	GpV Apex motif (Apex)	GpV Apex motif	-	Motif

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Baseplate assembly protein V	cation binding ion binding binding metal ion binding small molecule binding	symbiont-mediated disruption of host anatomical structure biological process involved in interspecies interaction between organisms viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated perturbation of host membrane symbiont genome entry into host cell via pore formation in plasma membrane symbiont-mediated disruption of host cellular anatomical entity symbiont entry into host cell viral process symbiont entry into host disruption of anatomical structure in another organism virion attachment to host cell receptor-mediated virion attachment to host cell symbiont-mediated disruption of host anatomical structure biological process involved in interspecies interaction between organisms viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated perturbation of host membrane symbiont genome entry into host cell via pore formation in plasma membrane symbiont-mediated disruption of host cellular anatomical entity symbiont entry into host cell viral process symbiont entry into host disruption of anatomical structure in another organism virion attachment to host cell receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell adhesion of symbiont to host virion assembly viral tail assembly	virus tail virion component virus tail, baseplate

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR006531	Gp5/Type VI secretion system Vgr protein, OB-fold domain	Domain
A, B	IPR044033	GpV-like, apex motif	Conserved Site
A, B	IPR013046	Phage baseplate assembly protein V/Gp45	Family
A, B	IPR037026	Vgr protein, OB-fold domain superfamily	Homologous Superfamily
A, B	IPR040629	Phage spike trimer	Domain

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.