3KQU
Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | PF22027 | e3kquA5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| A | F_UNCLASSIFIED | e3kquA4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| A | PF07652 | e3kquA2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
| B | PF22027 | e3kquB5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| B | F_UNCLASSIFIED | e3kquB4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| B | PF07652 | e3kquB2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
| C | PF22027 | e3kquC5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| C | F_UNCLASSIFIED | e3kquC4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| C | PF07652 | e3kquC2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
| D | PF22027 | e3kquD5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| D | F_UNCLASSIFIED | e3kquD4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| D | PF07652 | e3kquD2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
| E | PF22027 | e3kquE5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| E | F_UNCLASSIFIED | e3kquE4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| E | PF07652 | e3kquE2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
| F | PF22027 | e3kquF5 | A: alpha arrays | X: C-terminal helical domain of RNA helicase (From Topology) | H: C-terminal helical domain of RNA helicase (From Topology) | T: C-terminal helical domain of RNA helicase | F: PF22027 | ECOD (1.6) |
| F | F_UNCLASSIFIED | e3kquF4 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: F_UNCLASSIFIED | ECOD (1.6) |
| F | PF07652 | e3kquF2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: PF07652 | ECOD (1.6) |
