3JTD

Calcium-free Scallop Myosin Regulatory Domain with ELC-D19A Point Mutation

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3jtdb_	All alpha proteins	EF Hand-like	EF-hand	Calmodulin-like	automated matches	(Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)
C	d3jtdc_	All alpha proteins	EF Hand-like	EF-hand	Calmodulin-like	Myosin Regulatory Chain	Bay scallop (Argopecten irradians ) [TaxId: 31199 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	EF-hand	8037349	3001983	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	EF-hand	8037362	3001983	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	F_UNCLASSIFIED	e3jtdB4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
B	PF13499	e3jtdB3	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)
C	F_UNCLASSIFIED	e3jtdC4	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: F_UNCLASSIFIED	ECOD (1.6)
C	PF13499	e3jtdC3	A: alpha arrays	X: EF-hand	H: EF-hand-related	T: EF-hand	F: PF13499	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	4.10.270.10	Few Secondary Structures	Irregular	Myosin, subunit A	Myosin, subunit A	CATH (4.3.0)
B	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)
C	1.10.238.10	Mainly Alpha	Orthogonal Bundle	Recoverin	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain
C	PF13499	EF-hand domain pair (EF-hand_7)	EF-hand domain pair	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Myosin heavy chain, striated adductor muscle	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding cytoskeletal protein binding actin binding protein-containing complex binding protein binding actin filament binding calmodulin binding cytoskeletal motor activity microfilament motor activity ATP-dependent activity	cytoskeleton-dependent cytokinesis mitotic cytokinetic process mitotic cytokinesis mitotic actomyosin contractile ring contraction mitotic cell cycle cellular component organization contractile ring contraction cortical actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cell cycle cell cycle process actin cytoskeleton organization actomyosin structure organization cytoskeleton-dependent cytokinesis mitotic cytokinetic process mitotic cytokinesis mitotic actomyosin contractile ring contraction mitotic cell cycle cellular component organization contractile ring contraction cortical actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cell cycle cell cycle process actin cytoskeleton organization actomyosin structure organization cortical cytoskeleton organization cytokinesis organelle organization mitotic cell cycle process actomyosin contractile ring contraction cytokinetic process actomyosin contractile ring organization cellular process cell division cytoskeleton organization multicellular organismal process system process muscle contraction muscle system process cellular developmental process cellular component assembly involved in morphogenesis non-membrane-bounded organelle assembly cell development muscle cell differentiation cellular component biogenesis muscle structure development striated muscle cell development cellular anatomical entity morphogenesis cellular component assembly muscle cell development cell differentiation sarcomere organization anatomical structure development developmental process organelle assembly anatomical structure morphogenesis myofibril assembly anatomical structure formation involved in morphogenesis striated muscle cell differentiation supramolecular fiber organization	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle contractile muscle fiber cytoplasm supramolecular fiber myofibril supramolecular polymer supramolecular complex myosin filament contractile ring cell division site cell cortex cortical cytoskeleton actomyosin contractile ring mitotic actomyosin contractile ring cell periphery cortical actin cytoskeleton
B	Myosin regulatory light chain, striated adductor muscle	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding myosin heavy chain binding cytoskeletal protein binding protein binding myosin binding cytoskeletal motor regulator activity molecular function regulator activity	locomotion mitotic cell cycle process cytoskeleton-dependent cytokinesis mitotic cytokinesis cellular process cytokinesis cell division cell cycle mitotic cell cycle cell cycle process cellular component organization organelle organization actomyosin structure organization actin cytoskeleton organization locomotion mitotic cell cycle process cytoskeleton-dependent cytokinesis mitotic cytokinesis cellular process cytokinesis cell division cell cycle mitotic cell cycle cell cycle process cellular component organization organelle organization actomyosin structure organization actin cytoskeleton organization actin filament-based process cellular component organization or biogenesis cytoskeleton organization developmental process multicellular organism development multicellular organismal process anatomical structure development post-embryonic development	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle myosin II complex non-membrane-bounded organelle cytoplasm
C	Myosin essential light chain, striated adductor muscle	cation binding ion binding binding calcium ion binding metal ion binding small molecule binding	-	protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle contractile muscle fiber myosin II complex cytoplasm supramolecular fiber muscle myosin complex protein-containing complex intracellular anatomical structure cellular anatomical entity actin cytoskeleton myosin complex intracellular organelle cytoskeleton organelle intracellular non-membrane-bounded organelle contractile muscle fiber myosin II complex cytoplasm supramolecular fiber muscle myosin complex supramolecular polymer supramolecular complex non-membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036961	Kinesin motor domain superfamily	Homologous Superfamily
A	IPR014751	DNA repair protein XRCC4-like, C-terminal	Homologous Superfamily
A	IPR001609	Myosin head, motor domain	Domain
A	IPR002928	Myosin tail	Domain
A	IPR004009	Myosin, N-terminal, SH3-like	Domain
A	IPR008989	Myosin S1 fragment, N-terminal	Homologous Superfamily
A	IPR000048	IQ motif, EF-hand binding site	Binding Site
A	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
B	IPR018247	EF-Hand 1, calcium-binding site	Binding Site
B	IPR002048	EF-hand domain	Domain
B	IPR011992	EF-hand domain pair	Homologous Superfamily
C	IPR002048	EF-hand domain	Domain
C	IPR011992	EF-hand domain pair	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.