Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AEUF08555e3j17A1 A: a+b complex topologyX: Reovirus guanylyltransferase (GTase) (From Topology)H: Reovirus guanylyltransferase (GTase) (From Topology)T: Reovirus guanylyltransferase (GTase)F: EUF08555ECOD (1.6)
AEUF08556e3j17A2 A: a+b complex topologyX: Reovirus turret protein bridge domain (From Topology)H: Reovirus turret protein bridge domain (From Topology)T: Reovirus turret protein bridge domainF: EUF08556ECOD (1.6)
AEUF08594e3j17A3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: EUF08594ECOD (1.6)
AEUF08595e3j17A4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: S-adenosyl-L-methionine-dependent methyltransferasesF: EUF08595ECOD (1.6)
CEUF08564e3j17C1 A: a+b complex topologyX: Inner layer core protein p3-related (From Topology)H: Inner layer core protein p3-related (From Topology)T: Inner layer core protein p3-relatedF: EUF08564ECOD (1.6)
CEUF08644e3j17C2 A: a/b three-layered sandwichesX: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell protein (From Topology)H: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell protein (From Topology)T: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell proteinF: EUF08644ECOD (1.6)
BEUF08564e3j17B4 A: a+b complex topologyX: Inner layer core protein p3-related (From Topology)H: Inner layer core protein p3-related (From Topology)T: Inner layer core protein p3-relatedF: EUF08564ECOD (1.6)
BEUF08644e3j17B3 A: a/b three-layered sandwichesX: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell protein (From Topology)H: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell protein (From Topology)T: Small protrusion domain in cytoplasmic polyhedrosis virus capsid shell proteinF: EUF08644ECOD (1.6)
DEUF07968e3j17D1 A: alpha arraysX: Viral structural protein 5 (From Topology)H: Viral structural protein 5 (From Topology)T: Viral structural protein 5F: EUF07968ECOD (1.6)
EEUF07968e3j17E1 A: alpha arraysX: Viral structural protein 5 (From Topology)H: Viral structural protein 5 (From Topology)T: Viral structural protein 5F: EUF07968ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF20790Reovirus VP3 protein, guanylyltransferase (GTase) (Reov_VP3_GTase)Reovirus VP3 protein, guanylyltransferase (GTase)This domain family is found at the N-terminal end of Turret protein (TP), also known as VP3, from Reovirus. This GTase domain, responsible for the catalysis of the first step of RNA capping, consists of two subdomains, which form a deep and narrow cl ...This domain family is found at the N-terminal end of Turret protein (TP), also known as VP3, from Reovirus. This GTase domain, responsible for the catalysis of the first step of RNA capping, consists of two subdomains, which form a deep and narrow cleft. This domain is rich in beta strands and adopts a pentameric assembly [1,2].
Domain
PF20830Reovirus turret protein, bridge domain (Reovirus_bridge)Reovirus turret protein, bridge domainCytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanyl ...Cytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanylyltransferase (GTase) domain (Pfam:PF20790), two methylase domains and a bridge domain (this entry), which has two discontinuous regions [1,2].
Domain
PF20832Reovirus VP3 protein, Methyltransferase domain 2 (Reov_VP3_MTase2)Reovirus VP3 protein, Methyltransferase domain 2Cytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanyl ...Cytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanylyltransferase (GTase) domain (Pfam:PF20790), two methyltransferase domains and a bridge domain. This entry represents the second methyltransferase domain, which is found at the C-terminal end of the protein [1,2].
Domain
PF20831Reovirus VP3 protein, Methyltransferase domain 1 (Reov_VP3_MTase1)Reovirus VP3 protein, Methyltransferase domain 1Cytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanyl ...Cytoplasmic polyhedrosis virus (CPV) has a turreted single-layer capsid consisting of 12 pentameric turrets on the five-fold vertices. Each turret has one Turret protein (TP), also known as VP3, which shows a polyhedrin-binding domain (PBD), a guanylyltransferase (GTase) domain (Pfam:PF20790), two methyltransferase domains and a bridge domain. This entry represents the first methyltransferase domain (MTase-1), which has the small brace domain inserted on it [1,2].
Domain
B, C
PF20855CPV Capsid shell protein VP1, small protrusion domain (VP1_protrusion)CPV Capsid shell protein VP1, small protrusion domainThis domain is found in Capsid shell protein VP1 from Cytoplasmic polyhedrosis virus (CPV). VP1, one of the three major capsid proteins of CPV, has an overall thin-plate-like shape similar to its counterparts in other reoviruses except for a protrusi ...This domain is found in Capsid shell protein VP1 from Cytoplasmic polyhedrosis virus (CPV). VP1, one of the three major capsid proteins of CPV, has an overall thin-plate-like shape similar to its counterparts in other reoviruses except for a protrusion domain on the outer capsid surface, which is unique in single-layered cypoviruses [1].
Domain
B, C
PF21416Inner layer core protein VP1-like, C-terminal (VP1-like_C)Inner layer core protein VP1-like, C-terminalThis entry includes capsid proteins from cypoviruses which form the icosahedral capsid through self-assembly (they are also known as inner layer core proteins). The capsid encapsulates and protects the genomic RNA. These viruses encode VP1, VP3 and V ...This entry includes capsid proteins from cypoviruses which form the icosahedral capsid through self-assembly (they are also known as inner layer core proteins). The capsid encapsulates and protects the genomic RNA. These viruses encode VP1, VP3 and VP5 as major capsid proteins, encoded by RNA segment 1 and 3 in the case of VP1 and VP3, respectively, whereas RNA segment encoding VP5 is still unclear. This entry represents the C-terminal domain of capsid proteins from cypovirusus [1-3].
Domain
D, E
PF20807Viral structural protein 5 (VP5)Viral structural protein 5- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Structural protein VP3- - -
B, C
VP1- -
D, E
Structural protein VP5- - -

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
GPL Parent Component: LYS

RESIDAA0228

PSI-MOD :  N6-(phospho-5'-guanosine)-L-lysine MOD:00233