Annotations: 3I27

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Hema_esterase_2nd	e3i27A1	A: beta sandwiches	X: jelly-roll	H: Viral protein domain (From Topology)	T: Viral protein domain	F: Hema_esterase_2nd	ECOD (1.6)
A	Hema_esterase_1st	e3i27A2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Hema_esterase_1st	ECOD (1.6)
B	Hema_esterase_2nd	e3i27B4	A: beta sandwiches	X: jelly-roll	H: Viral protein domain (From Topology)	T: Viral protein domain	F: Hema_esterase_2nd	ECOD (1.6)
B	Hema_esterase_1st	e3i27B3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Hema_esterase_1st	ECOD (1.6)
C	Hema_esterase_2nd	e3i27C4	A: beta sandwiches	X: jelly-roll	H: Viral protein domain (From Topology)	T: Viral protein domain	F: Hema_esterase_2nd	ECOD (1.6)
C	Hema_esterase_1st	e3i27C3	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Hema_esterase_1st	ECOD (1.6)
D	Hema_esterase_2nd	e3i27D1	A: beta sandwiches	X: jelly-roll	H: Viral protein domain (From Topology)	T: Viral protein domain	F: Hema_esterase_2nd	ECOD (1.6)
D	Hema_esterase_1st	e3i27D2	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: SGNH hydrolase (From Topology)	T: SGNH hydrolase	F: Hema_esterase_1st	ECOD (1.6)

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF03996	Hemagglutinin esterase (Hema_esterase)	Hemagglutinin esterase	-	Domain
A, B, C, D	PF02710	Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein (Hema_HEFG)	Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein	-	Family

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Hemagglutinin-esterase	binding carbohydrate binding hydrolase activity, acting on ester bonds short-chain carboxylesterase activity carboxylic ester hydrolase activity acetylesterase activity hydrolase activity sialate O-acetylesterase activity catalytic activity sialate 9-O-acetylesterase activity sialate 4-O-acetylesterase activity host cell surface binding host cell surface receptor binding	membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell	membrane cellular anatomical entity virion component virion membrane viral membrane viral envelope host cell plasma membrane host cellular component host cell part host cell membrane

Chains	Accession	Name	Type
A, B, C, D	IPR008980	Viral capsid/haemagglutinin protein	Homologous Superfamily
A, B, C, D	IPR003860	Haemagglutinin-esterase glycoprotein, haemagglutinin domain	Domain
A, B, C, D	IPR007142	Haemagglutinin-esterase glycoprotein, core	Domain