Annotations: 3GWL

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3gwla1	All alpha proteins	Four-helical up-and-down bundle	FAD-dependent thiol oxidase	automated matches	automated matches	ASFV (African swine fever virus BA71V ) [TaxId: 10498 ],	SCOPe (2.08)
A	d3gwla2	Artifacts	Tags	Tags	Tags	N-terminal Tags	ASFV (African swine fever virus BA71V ) [TaxId: 10498 ],	SCOPe (2.08)
B	d3gwlb1	All alpha proteins	Four-helical up-and-down bundle	FAD-dependent thiol oxidase	automated matches	automated matches	ASFV (African swine fever virus BA71V ) [TaxId: 10498 ],	SCOPe (2.08)
B	d3gwlb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	ASFV (African swine fever virus BA71V ) [TaxId: 10498 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF04777	e3gwlA1	A: alpha bundles	X: Four-helical up-and-down bundle	H: FAD-dependent thiol oxidase (From Topology)	T: FAD-dependent thiol oxidase	F: PF04777	ECOD (1.6)
B	PF04777	e3gwlB1	A: alpha bundles	X: Four-helical up-and-down bundle	H: FAD-dependent thiol oxidase (From Topology)	T: FAD-dependent thiol oxidase	F: PF04777	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.120.310	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	ERV/ALR sulfhydryl oxidase domain	CATH (4.3.0)
B	1.20.120.310	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	ERV/ALR sulfhydryl oxidase domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF04777	Erv1 / Alr family (Evr1_Alr)	Erv1 / Alr family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	FAD-linked sulfhydryl oxidase	oxidoreductase activity, acting on a sulfur group of donors disulfide oxidoreductase activity oxidoreductase activity catalytic activity, acting on a protein oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor protein-disulfide reductase activity flavin-dependent sulfhydryl oxidase activity thiol oxidase activity catalytic activity	-	virion component host cellular component host intracellular part host cell cytoplasm host cell part host intracellular region cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR036774	ERV/ALR sulfhydryl oxidase domain superfamily	Homologous Superfamily
A, B	IPR017905	ERV/ALR sulfhydryl oxidase domain	Domain
A, B	IPR039799	Sulfhydryl oxidase ALR/ERV	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.