3GGX
HIV Protease, pseudo-symmetric inhibitors
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
G | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
H | SCOP2B Superfamily | Acid proteases | 8072209 | 3001059 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
G | PF00077 | e3ggxG1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
A | PF00077 | e3ggxA1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
B | PF00077 | e3ggxB1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
C | PF00077 | e3ggxC1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
D | PF00077 | e3ggxD1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
E | PF00077 | e3ggxE1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
F | PF00077 | e3ggxF1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
H | PF00077 | e3ggxH1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: acid protease | F: PF00077 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
G | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
A | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
B | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
C | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
D | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
E | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
F | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
H | 2.40.70.10 | Mainly Beta | Beta Barrel | Cathepsin D, subunit A | domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00077 | Retroviral aspartyl protease (RVP) | Retroviral aspartyl protease | Single domain aspartyl proteases from retroviruses, retrotransposons, and badnaviruses (plant dsDNA viruses). These proteases are generally part of a larger polyprotein; usually pol, more rarely gag. Retroviral proteases appear to be homologous to a ... | Domain |