2ZI8
Crystal structure of the HsaC extradiol dioxygenase from M. tuberculosis in complex with 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (DHSA)
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d2zi8a1 | Alpha and beta proteins (a+b) | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | automated matches | automated matches | (Mycobacterium tuberculosis ) [TaxId: 1773 ], | SCOPe (2.08) |
B | d2zi8b1 | Alpha and beta proteins (a+b) | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | automated matches | automated matches | (Mycobacterium tuberculosis ) [TaxId: 1773 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | F_UNCLASSIFIED | e2zi8A13 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: F_UNCLASSIFIED | ECOD (1.6) |
A | PF00903 | e2zi8A1 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: PF00903 | ECOD (1.6) |
A | PF22632 | e2zi8A12 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: PF22632 | ECOD (1.6) |
B | F_UNCLASSIFIED | e2zi8B1 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: F_UNCLASSIFIED | ECOD (1.6) |
B | PF00903 | e2zi8B4 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: PF00903 | ECOD (1.6) |
B | PF22632 | e2zi8B2 | A: a+b two layers | X: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | H: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (From Topology) | T: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | F: PF22632 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.10.180.10 | Alpha Beta | Roll | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase | domain 1 | CATH (4.3.0) |
B | 3.10.180.10 | Alpha Beta | Roll | 2,3-Dihydroxybiphenyl 1,2-Dioxygenase | domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00903 | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (Glyoxalase) | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000486 | Extradiol ring-cleavage dioxygenase, class I /II | Conserved Site | |
IPR029068 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Homologous Superfamily | |
IPR037523 | Vicinal oxygen chelate (VOC) domain | Domain | |
IPR004360 | Glyoxalase/fosfomycin resistance/dioxygenase domain | Domain |