2X9A

crystal structure of g3p from phage IF1 in complex with its coreceptor, the C-terminal domain of TolA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2x9aa_	All beta proteins	N-terminal domains of the minor coat protein g3p	N-terminal domains of the minor coat protein g3p	automated matches	automated matches	(Escherichia phage If1 ) [TaxId: 10868 ],	SCOPe (2.08)
C	d2x9ac_	All beta proteins	N-terminal domains of the minor coat protein g3p	N-terminal domains of the minor coat protein g3p	automated matches	automated matches	(Escherichia phage If1 ) [TaxId: 10868 ],	SCOPe (2.08)
D	d2x9ad1	Alpha and beta proteins (a+b)	TolA/TonB C-terminal domain	TolA/TonB C-terminal domain	TolA	automated matches	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
D	d2x9ad2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d2x9ab1	Alpha and beta proteins (a+b)	TolA/TonB C-terminal domain	TolA/TonB C-terminal domain	TolA	automated matches	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d2x9ab2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	N-terminal domains of the minor coat protein g3p	8098228	3000411	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	N-terminal domains of the minor coat protein g3p	8098228	3000411	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	TolA/TonB C-terminal domain-like	8101715	3000464	SCOP2B (2022-06-29)
B	SCOP2 Family	TolA	8101714	4001432	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	TolA/TonB C-terminal domain-like	8101715	3000464	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF05357	e2x9aA1	A: beta meanders	X: N-terminal domains of the minor coat protein g3p (From Topology)	H: N-terminal domains of the minor coat protein g3p (From Topology)	T: N-terminal domains of the minor coat protein g3p	F: PF05357	ECOD (1.6)
C	PF05357	e2x9aC1	A: beta meanders	X: N-terminal domains of the minor coat protein g3p (From Topology)	H: N-terminal domains of the minor coat protein g3p (From Topology)	T: N-terminal domains of the minor coat protein g3p	F: PF05357	ECOD (1.6)
D	PF06519	e2x9aD1	A: a+b two layers	X: TolA/TonB C-terminal domain	H: TolA/TonB C-terminal domain (From Topology)	T: TolA/TonB C-terminal domain	F: PF06519	ECOD (1.6)
B	PF06519	e2x9aB1	A: a+b two layers	X: TolA/TonB C-terminal domain	H: TolA/TonB C-terminal domain (From Topology)	T: TolA/TonB C-terminal domain	F: PF06519	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.30.27.10	Mainly Beta	Roll	Phage FD Coat Protein, Membrane penetration domain	Phage FD Coat Protein,Membrane penetration domain	CATH (4.3.0)
C	2.30.27.10	Mainly Beta	Roll	Phage FD Coat Protein, Membrane penetration domain	Phage FD Coat Protein,Membrane penetration domain	CATH (4.3.0)
D	3.30.1150.10	Alpha Beta	2-Layer Sandwich	Fusion Protein Consisting Of Minor Coat Protein, Glycine Rich Linker, Tola, And A His Tag	Chain: A	CATH (4.3.0)
B	3.30.1150.10	Alpha Beta	2-Layer Sandwich	Fusion Protein Consisting Of Minor Coat Protein, Glycine Rich Linker, Tola, And A His Tag	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF05357	Phage Coat Protein A (Phage_Coat_A)	Phage Coat Protein A	Infection of Escherichia coli by filamentous bacteriophages is mediated by the minor phage coat protein A and involves two distinct cellular receptors, the F' pilus and the periplasmic protein TolA. These two receptors are contacted in a sequential ...	Infection of Escherichia coli by filamentous bacteriophages is mediated by the minor phage coat protein A and involves two distinct cellular receptors, the F' pilus and the periplasmic protein TolA. These two receptors are contacted in a sequential manner, such that binding of TolA by the extreme N-terminal domain is conditional on a primary interaction of the second coat protein A domain with the F' pilus [1].	Domain
B, D	PF06519	TolA C-terminal (TolA)	TolA C-terminal	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	ATTACHMENT PROTEIN G3P	-	virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell viral process viral life cycle adhesion of symbiont to host adhesion receptor-mediated virion attachment to host cell biological process involved in interaction with host biological process involved in symbiotic interaction exit from host cell non-lytic viral release viral extrusion viral release from host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell viral process viral life cycle adhesion of symbiont to host adhesion receptor-mediated virion attachment to host cell biological process involved in interaction with host biological process involved in symbiotic interaction exit from host cell non-lytic viral release viral extrusion viral release from host cell entry receptor-mediated virion attachment to host cell virion attachment to host cell pilus symbiont entry into host cell symbiont entry into host	viral capsid virion component host cellular component host cell part host cell membrane cellular anatomical entity membrane
B, D	MEMBRANE SPANNING PROTEIN, REQUIRED FOR OUTER MEMBRANE INTEGRITY	toxin transmembrane transporter activity transporter activity transmembrane transporter activity	localization nitrogen compound transport amide transport transport organic substance transport bacteriocin transport establishment of localization	membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR036200	Attachment protein G3P, N-terminal domain superfamily	Homologous Superfamily
A, C	IPR008021	Attachment protein G3P, N-terminal	Domain
B, D	IPR014161	Tol-Pal system, TolA	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.