Annotations: 2WCC

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth 3]	SCOP2B Superfamily	DNA-binding domain	8035081	3000183	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth 3]	Arm-DNA-bind_1	e2wcc31	A: a+b two layers	X: DNA-binding domain	H: GCC-box binding domain-like (From Topology)	T: GCC-box binding domain-like	F: Arm-DNA-bind_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C [auth 3]	3.30.160.60	Alpha Beta	2-Layer Sandwich	Double Stranded RNA Binding Domain	Classic Zinc Finger	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth 3]	PF09003	Bacteriophage lambda integrase, Arm DNA-binding domain (Arm-DNA-bind_1)	Bacteriophage lambda integrase, Arm DNA-binding domain	The amino terminal domain of bacteriophage lambda integrase folds into a three-stranded, antiparallel beta-sheet that packs against a C-terminal alpha-helix, adopting a fold that is structurally related to the three-stranded beta-sheet family of DNA- ...	The amino terminal domain of bacteriophage lambda integrase folds into a three-stranded, antiparallel beta-sheet that packs against a C-terminal alpha-helix, adopting a fold that is structurally related to the three-stranded beta-sheet family of DNA-binding domains (which includes the GCC-box DNA-binding domain and the N-terminal domain of Tn916 integrase). This domain is responsible for high-affinity binding to each of the five DNA arm-type sites and is also a context-sensitive modulator of DNA cleavage [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 1]	DNA (5'-D(DCPDGPDAPDGPDTPDCPDAP DAPDAPDAPDTPDC)-3')	-	-	-
B [auth 2]	DNA (5'-D(DGPDAPDTPDTPDTPDTPDGP DAPDCPDTPDGPDC)-3')	-	-	-
C [auth 3]	INTEGRASE	DNA binding binding organic cyclic compound binding nucleic acid binding hydrolase activity catalytic activity transferase activity integrase activity catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid	establishment of integrated proviral latency viral latency viral process establishment of viral latency biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process establishment of integrated proviral latency viral latency viral process establishment of viral latency biological process involved in interspecies interaction between organisms symbiont entry into host cell symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process DNA integration nucleic acid metabolic process viral genome integration into host DNA DNA recombination provirus excision latent virus replication release from viral latency	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth 3]	IPR011010	DNA breaking-rejoining enzyme, catalytic core	Homologous Superfamily
C [auth 3]	IPR010998	Integrase/recombinase, N-terminal	Homologous Superfamily
C [auth 3]	IPR015094	Integrase, lambda-type, N-terminal DNA-binding	Domain
C [auth 3]	IPR044068	Core-binding (CB) domain	Domain
C [auth 3]	IPR002104	Integrase, catalytic domain	Domain
C [auth 3]	IPR004107	Integrase, SAM-like, N-terminal	Domain
C [auth 3]	IPR013762	Integrase-like, catalytic domain superfamily	Homologous Superfamily
C [auth 3]	IPR016177	DNA-binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.