2N2J

Solution structure of the EBNA-2 N-terminal Dimerization (END) domain from the Epstein-barr virus

External Resource: Annotation

Domain Annotation: ECOD Classification
Gene Ontology: Gene Product Annotation

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	UNK_F_TYPE	e2n2jA1	A: beta duplicates or obligate multimers	X: EBNA-2 N-terminal dimerization (END) domain (From Topology)	H: EBNA-2 N-terminal dimerization (END) domain (From Topology)	T: EBNA-2 N-terminal dimerization (END) domain	F: UNK_F_TYPE	ECOD (1.6)
B	UNK_F_TYPE	e2n2jB1	A: beta duplicates or obligate multimers	X: EBNA-2 N-terminal dimerization (END) domain (From Topology)	H: EBNA-2 N-terminal dimerization (END) domain (From Topology)	T: EBNA-2 N-terminal dimerization (END) domain	F: UNK_F_TYPE	ECOD (1.6)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Epstein-Barr nuclear antigen 2	enzyme regulator activity phosphatase inhibitor activity molecular function inhibitor activity phosphatase regulator activity molecular function regulator activity protein phosphatase regulator activity protein phosphatase inhibitor activity enzyme inhibitor activity protein serine/threonine phosphatase inhibitor activity	viral gene expression DNA-templated viral transcription viral process viral transcription symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms symbiont-mediated perturbation of host translation biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated suppression of host gene expression symbiont-mediated suppression of host translation initiation modulation by symbiont of host process symbiont-mediated suppression of host translation symbiont-mediated perturbation of host gene expression viral gene expression DNA-templated viral transcription viral process viral transcription symbiont-mediated perturbation of host cellular process biological process involved in interspecies interaction between organisms symbiont-mediated perturbation of host translation biological process involved in interaction with host biological process involved in symbiotic interaction symbiont-mediated suppression of host gene expression symbiont-mediated suppression of host translation initiation modulation by symbiont of host process symbiont-mediated suppression of host translation symbiont-mediated perturbation of host gene expression cellular process modulation of process of another organism regulation of cellular process positive regulation of macromolecule biosynthetic process regulation of primary metabolic process nucleobase-containing compound metabolic process positive regulation of metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process positive regulation of macromolecule metabolic process regulation of nucleobase-containing compound metabolic process regulation of biological process positive regulation of nucleobase-containing compound metabolic process cellular metabolic process primary metabolic process regulation of cellular metabolic process positive regulation of RNA metabolic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process positive regulation of DNA-templated transcription cellular biosynthetic process positive regulation of biological process RNA metabolic process positive regulation of cellular metabolic process RNA biosynthetic process nucleic acid biosynthetic process organic substance metabolic process positive regulation of biosynthetic process positive regulation of cellular process regulation of RNA biosynthetic process regulation of biosynthetic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process positive regulation of RNA biosynthetic process positive regulation of cellular biosynthetic process symbiont-mediated suppression of host type I interferon-mediated signaling pathway symbiont-mediated suppression of host signal transduction pathway symbiont-mediated suppression of host interferon-mediated signaling pathway symbiont-mediated perturbation of host signal transduction pathway	host intracellular membrane-bounded organelle host cellular component host cell nuclear matrix host intracellular part host cell part host intracellular region cellular anatomical entity host cell nucleus host cell nuclear part host intracellular organelle

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.