2K6X

Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2k6xa1	All alpha proteins	DNA/RNA-binding 3-helical bundle	Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma4 domain	Sigma70 (SigA, RpoD)	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)
A	d2k6xa2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Thermotoga maritima ) [TaxId: 2336 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF03979	e2k6xA1	A: alpha arrays	X: RNA polymerase sigma factor rpoD N-terminal domain (From Topology)	H: RNA polymerase sigma factor rpoD N-terminal domain (From Topology)	T: RNA polymerase sigma factor rpoD N-terminal domain	F: PF03979	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.220.120	Mainly Alpha	Orthogonal Bundle	Annexin V	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF03979	Sigma-70 factor, region 1.1 (Sigma70_r1_1)	Sigma-70 factor, region 1.1	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	RNA polymerase sigma factor rpoD	DNA binding binding organic cyclic compound binding nucleic acid binding transcription regulator activity DNA-binding transcription factor activity sigma factor activity	cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription organic cyclic compound metabolic process nucleic acid biosynthetic process organic substance metabolic process cellular biosynthetic process cellular metabolic process RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription organic cyclic compound metabolic process nucleic acid biosynthetic process organic substance metabolic process biosynthetic process organic cyclic compound biosynthetic process organic substance biosynthetic process metabolic process cellular process macromolecule metabolic process	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR007627	RNA polymerase sigma-70 region 2	Domain
A	IPR007127	RNA polymerase sigma factor 70, region 1.1	Domain
A	IPR000943	RNA polymerase sigma-70	Domain
A	IPR013325	RNA polymerase sigma factor, region 2	Homologous Superfamily
A	IPR013324	RNA polymerase sigma factor, region 3/4-like	Homologous Superfamily
A	IPR036388	Winged helix-like DNA-binding domain superfamily	Homologous Superfamily
A	IPR012760	RNA polymerase sigma factor RpoD, C-terminal	Domain
A	IPR009042	RNA polymerase sigma-70 region 1.2	Domain
A	IPR007630	RNA polymerase sigma-70 region 4	Domain
A	IPR014284	RNA polymerase sigma-70-like domain	Domain
A	IPR007624	RNA polymerase sigma-70 region 3	Domain
A	IPR028630	RNA polymerase sigma factor RpoD	Family
A	IPR042189	Sigma-70 factor, region 1.1 superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.