2GE8

Structure of the C-terminal dimerization domain of infectious bronchitis virus nucleocapsid protein

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2ge8a1	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
B	d2ge8b_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
C [auth F]	d2ge8f_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
D [auth G]	d2ge8g_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
E [auth C]	d2ge8c_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
F [auth D]	d2ge8d_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
G [auth I]	d2ge8i_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)
H [auth J]	d2ge8j_	Alpha and beta proteins (a+b)	Nucleocapsid protein dimerization domain	Nucleocapsid protein dimerization domain	Coronavirus nucleocapsid protein	Coronavirus nucleocapsid protein	(Infectious bronchitis virus ) [TaxId: 11120 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
C [auth F]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
E [auth C]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
F [auth D]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
G [auth I]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)
H [auth J]	SCOP2B Superfamily	Nucleocapsid protein dimerization domain	8041817	3001606	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00937	e2ge8A1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
B	PF00937	e2ge8B1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
C [auth F]	PF00937	e2ge8F1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
D [auth G]	PF00937	e2ge8G1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
E [auth C]	PF00937	e2ge8C1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
F [auth D]	PF00937	e2ge8D1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
G [auth I]	PF00937	e2ge8I1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)
H [auth J]	PF00937	e2ge8J1	A: a+b duplicates or obligate multimers	X: Arterivirus nucleocapsid protein (From Topology)	H: Arterivirus nucleocapsid protein (From Topology)	T: Arterivirus nucleocapsid protein	F: PF00937	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	PF00937	Coronavirus nucleocapsid (CoV_nucleocap)	Coronavirus nucleocapsid	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	Nucleocapsid protein	RNA binding binding organic cyclic compound binding nucleic acid binding identical protein binding protein binding	-	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell endoplasmic reticulum-Golgi intermediate compartment host cell cytoplasm host cell part host intracellular region cellular anatomical entity host cell cytoplasm part host intracellular organelle protein-containing complex ribonucleoprotein complex viral nucleocapsid viral capsid host intracellular membrane-bounded organelle host cellular component host intracellular part host cell endoplasmic reticulum-Golgi intermediate compartment host cell cytoplasm host cell part host intracellular region cellular anatomical entity host cell cytoplasm part host intracellular organelle protein-containing complex ribonucleoprotein complex viral nucleocapsid viral capsid virion component host cell Golgi apparatus

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR001218	Nucleocapsid protein, coronavirus	Family
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR044344	Nucleocapsid (N) protein, C-terminal domain, coronavirus	Domain
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR042547	Nucleocapsid protein, gammacoronavirus	Family
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR037195	Nucleocapsid protein, N-terminal	Homologous Superfamily
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR037179	Nucleocapsid protein, C-terminal	Homologous Superfamily
A, B, C [auth F], D [auth G], E [auth C], A, B, C [auth F], D [auth G], E [auth C], F [auth D], G [auth I], H [auth J]	IPR044345	Nucleocapsid (N) protein, N-terminal domain, coronavirus	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.