2C5R

The structure of phage phi29 replication organizer protein p16.7 in complex with double stranded DNA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
F	d2c5rf_	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	automated matches	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)
A	d2c5ra1	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	Early protein gp16.7	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)
B	d2c5rb_	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	automated matches	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)
C	d2c5rc_	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	automated matches	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)
D	d2c5rd_	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	automated matches	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)
E	d2c5re_	All alpha proteins	Phage replication organizer domain	Phage replication organizer domain	Phage replication organizer domain	automated matches	(Salasvirus phi29 ) [TaxId: 10756 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
F	SCOP2B Superfamily	GP16.7-like	8039416	3001601	SCOP2B (2022-06-29)
A	SCOP2 Family	GP16.7-like	8027037	4001445	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	GP16.7-like	8039416	3001601	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	GP16.7-like	8039416	3001601	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	GP16.7-like	8039416	3001601	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	GP16.7-like	8039416	3001601	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	GP16.7-like	8039416	3001601	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
F	PF06720	e2c5rF1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)
A	PF06720	e2c5rA1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)
B	PF06720	e2c5rB1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)
C	PF06720	e2c5rC1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)
D	PF06720	e2c5rD1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)
E	PF06720	e2c5rE1	A: alpha arrays	X: Phage replication organizer domain (From Topology)	H: Phage replication organizer domain (From Topology)	T: Phage replication organizer domain	F: PF06720	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
F	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
A	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
B	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
C	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
D	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)
E	1.10.8.600	Mainly Alpha	Orthogonal Bundle	Helicase, Ruva Protein	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF06720	Bacteriophage phi-29 early protein GP16.7 (Phi-29_GP16_7)	Bacteriophage phi-29 early protein GP16.7	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	EARLY PROTEIN P16.7	DNA binding binding organic cyclic compound binding nucleic acid binding	nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process DNA replication organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process nucleic acid metabolic process cellular biosynthetic process cellular metabolic process viral DNA genome replication viral life cycle nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid biosynthetic process biosynthetic process viral genome replication organic cyclic compound biosynthetic process organic substance biosynthetic process viral process cellular process DNA biosynthetic process	host cellular component host cell part host cell membrane cellular anatomical entity membrane host cell plasma membrane
G [auth Y]	5'-D(TPCPCPAPCPCPGPGP)-3'	-	-	-
H [auth Z]	5'-D(CPCPGPGPTPGPGPAP)-3'	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR009595	Bacteriophage DNA replication protein Gp16.7	Family
A, B, C, D, E A, B, C, D, E, F	IPR037211	Bacteriophage DNA replication protein Gp16.7 superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.