Annotations: 1YU3

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1yu3a1	All beta proteins	Pseudo beta-prism I	Bacteriophage trimeric proteins domain	Mtd domain-like	Major tropism determinant (Mtd), N-terminal domain	(Bordetella phage BIP-1 ) [TaxId: 263375 ],	SCOPe (2.08)
A	d1yu3a2	Alpha and beta proteins (a+b)	C-type lectin-like	C-type lectin-like	Mtd variable domain	Major tropism determinant (Mtd), C-terminal domain	(Bordetella phage BIP-1 ) [TaxId: 263375 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Bacteriophage trimeric proteins domain	8034885	3000915	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	C-type lectin-like	8034887	3001261	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	mtd_2nd	e1yu3A2	A: beta sandwiches	X: Lactophage receptor-binding protein N-terminal domain-like (From Topology)	H: Lactophage receptor-binding protein N-terminal domain-like (From Topology)	T: Lactophage receptor-binding protein N-terminal domain-like	F: mtd_2nd	ECOD (1.6)
A	mtd_1st	e1yu3A4	A: beta duplicates or obligate multimers	X: Major tropism determinant (Mtd) trimerization domain-related (From Topology)	H: Major tropism determinant (Mtd) trimerization domain-related (From Topology)	T: Major tropism determinant (Mtd) trimerization domain-related	F: mtd_1st	ECOD (1.6)
A	FGE-sulfatase_1	e1yu3A3	A: a+b complex topology	X: C-type lectin-like (From Homology)	H: C-type lectin-like	T: Sulfatase-modifying factor-like	F: FGE-sulfatase_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.10.10.30	Mainly Beta	Ribbon	Seminal Fluid Protein PDC-109 (Domain B)		CATH (4.3.0)
A	2.80.20.10	Mainly Beta	Trefoil	Tail fiber receptor-binding protein	Tail fiber receptor-binding protein	CATH (4.3.0)
A	3.90.1580.10	Alpha Beta	Alpha-Beta Complex	paralog of FGE (formylglycine-generating enzyme)	paralog of FGE (formylglycine-generating enzyme)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF18454	Major tropism determinant N-terminal domain (Mtd_N)	Major tropism determinant N-terminal domain	This is the N-terminal domain of major tropism determinant (Mtd), a retroelement-encoded receptor-binding protein. Mtd-N forms a three-fold symmetric beta-prism. This resembles the pseudo three-fold-symmetric beta-prisms of monocot lectins, but lacks ...	This is the N-terminal domain of major tropism determinant (Mtd), a retroelement-encoded receptor-binding protein. Mtd-N forms a three-fold symmetric beta-prism. This resembles the pseudo three-fold-symmetric beta-prisms of monocot lectins, but lacks residues in these lectins identified as binding carbohydrates. The beta-prism and beta-sandwich domains reinforce overall trimeric assembly and therefore may have indirect roles in stabilizing the backbone of the variable region [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Major Tropism Determinant (Mtd-I1)	-	biological process involved in interspecies interaction between organisms symbiont entry into host cell viral process symbiont entry into host viral life cycle biological process involved in interaction with host biological process involved in symbiotic interaction virion attachment to host cell receptor-mediated virion attachment to host cell adhesion of symbiont to host cell adhesion of symbiont to host adhesion receptor-mediated virion attachment to host cell viral tropism switching	virus tail, fiber virus tail virion component

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR042095	Sulfatase-modifying factor enzyme superfamily	Homologous Superfamily
A	IPR041352	Major tropism determinant, N-terminal domain	Domain
A	IPR016187	C-type lectin fold	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.