1YRH

Crystal Structure Of Trp Repressor Binding Protein Wrba in complex with FMN

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1yrha1	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
A	d1yrha2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
B	d1yrhb2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
B	d1yrhb3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
C	d1yrhc2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
C	d1yrhc3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
D	d1yrhd2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
D	d1yrhd3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
E	d1yrhe_	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
F	d1yrhf2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
F	d1yrhf3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
G	d1yrhg2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
G	d1yrhg3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
H	d1yrhh2	Alpha and beta proteins (a/b)	Flavodoxin-like	Flavoproteins	WrbA-like	Trp repressor binding protein WrbA	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)
H	d1yrhh3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Deinococcus radiodurans ) [TaxId: 1299 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Flavoproteins	8044299	3001217	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PF00258	e1yrhA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
B	PF00258	e1yrhB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
C	PF00258	e1yrhC1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
D	PF00258	e1yrhD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
E	PF00258	e1yrhE1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
F	PF00258	e1yrhF1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
G	PF00258	e1yrhG1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)
H	PF00258	e1yrhH1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Flavoproteins/Phosphotyrosine protein phosphatases-like	T: Flavoproteins	F: PF00258	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
B	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
C	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
D	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
E	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
F	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
G	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)
H	3.40.50.360	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Flavodoxin domain	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00258	Flavodoxin (Flavodoxin_1)	Flavodoxin	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	trp repressor binding protein WrbA	binding nucleotide binding FMN binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding oxidoreductase activity NAD(P)H dehydrogenase (quinone) activity oxidoreductase activity, acting on NAD(P)H binding nucleotide binding FMN binding nucleoside phosphate binding ion binding organic cyclic compound binding anion binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding oxidoreductase activity NAD(P)H dehydrogenase (quinone) activity oxidoreductase activity, acting on NAD(P)H oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor catalytic activity NADPH dehydrogenase (quinone) activity NADH:ubiquinone reductase (non-electrogenic) activity NADH dehydrogenase activity	-	membrane cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR010089	Flavoprotein WrbA-like	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR029039	Flavoprotein-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR005025	NADPH-dependent FMN reductase-like	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR008254	Flavodoxin/nitric oxide synthase	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.