Navigation Tabs
Solution structures of the SH3 domain of human rho guanine exchange factor (GEF) 16 External Resource: Annotation Domain Annotation: SCOP2 Classification SCOP2 Database Homepage Chains Type Family Name Domain Identifier Family Identifier Provenance Source (Version) A SCOP2 Family SH3-domain 8062114 4000369 SCOP2 (2022-06-29) A SCOP2 Superfamily SH3-domain 8062115 3000153 SCOP2 (2022-06-29)
Chains Family Name Domain Identifier Architecture Possible Homology Homology Topology Family Provenance Source (Version) A PF00018 e1x6bA1 A: beta barrels X: SH3 H: SH3 T: SH3 F: PF00018 ECOD (1.6)
Chains Accession Name Description Comments Source PF00018 SH3 domain (SH3_1) SH3 domain SH3 (Src homology 3) domains are often indicative of a protein involved in signal transduction related to cytoskeletal organisation. First described in the Src cytoplasmic tyrosine kinase Swiss:P12931. The structure is a partly opened beta barrel. Domain
Chains Polymer Molecular Function Biological Process Cellular Component Rho guanine exchange factor (GEF) 16
Chains Drug Target   Associated Disease Pharos :  Q5VV41