1UDI

NUCLEOTIDE MIMICRY IN THE CRYSTAL STRUCTURE OF THE URACIL-DNA GLYCOSYLASE-URACIL GLYCOSYLASE INHIBITOR PROTEIN COMPLEX

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A [auth E]	d1udie_	Alpha and beta proteins (a/b)	Uracil-DNA glycosylase-like	Uracil-DNA glycosylase-like	Uracil-DNA glycosylase	Uracil-DNA glycosylase	(Human alphaherpesvirus 1 strain 17 ) [TaxId: 10299 ],	SCOPe (2.08)
B [auth I]	d1udii_	Alpha and beta proteins (a+b)	Cystatin-like	Uracil-DNA glycosylase inhibitor protein	Uracil-DNA glycosylase inhibitor protein	Uracil-DNA glycosylase inhibitor protein	(Takahashivirus PBS1 ) [TaxId: 10683 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth E]	SCOP2B Superfamily	Uracil-DNA glycosylase-like	8044006	3001106	SCOP2B (2022-06-29)
B [auth I]	SCOP2B Superfamily	Uracil-DNA glycosylase inhibitor protein	8034693	3000500	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth E]	PF03167	e1udiE1	A: a/b three-layered sandwiches	X: Uracil-DNA glycosylase-like (From Topology)	H: Uracil-DNA glycosylase-like (From Topology)	T: Uracil-DNA glycosylase-like	F: PF03167	ECOD (1.6)
B [auth I]	PF18880	e1udiI1	A: a+b two layers	X: Cystatin-like	H: Uracil-DNA glycosylase inhibitor protein (From Topology)	T: Uracil-DNA glycosylase inhibitor protein	F: PF18880	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth E]	3.40.470.10	Alpha Beta	3-Layer(aba) Sandwich	Uracil-DNA Glycosylase, subunit E	Uracil-DNA glycosylase-like domain	CATH (4.3.0)
B [auth I]	3.10.450.20	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth E]	PF03167	Uracil DNA glycosylase superfamily (UDG)	Uracil DNA glycosylase superfamily	-	Domain
B [auth I]	PF18880	Uracil-DNA glycosylase inhibitor (UDI)	Uracil-DNA glycosylase inhibitor	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth E]	URACIL-DNA GLYCOSYLASE	uracil DNA N-glycosylase activity hydrolase activity, acting on glycosyl bonds deaminated base DNA N-glycosylase activity catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid hydrolase activity DNA N-glycosylase activity hydrolase activity, hydrolyzing N-glycosyl compounds catalytic activity	cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process base-excision repair organic substance metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process organic cyclic compound metabolic process base-excision repair organic substance metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair	host intracellular membrane-bounded organelle host cellular component host intracellular part host cell part host intracellular region cellular anatomical entity host cell nucleus host intracellular organelle
B [auth I]	URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth E]	IPR002043	Uracil-DNA glycosylase family 1	Family
A [auth E]	IPR018085	Uracil-DNA glycosylase, active site	Active Site
A [auth E]	IPR036895	Uracil-DNA glycosylase-like domain superfamily	Homologous Superfamily
A [auth E]	IPR005122	Uracil-DNA glycosylase-like	Domain
B [auth I]	IPR024062	Bacteriophage PBS2, uracil-glycosylase inhibitor	Homologous Superfamily
B [auth I]	IPR043805	Uracil-DNA glycosylase inhibitor	Family

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.