Annotations: 1OUQ

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
G [auth A]	d1ouqa1	All alpha proteins	SAM domain-like	lambda integrase-like, N-terminal domain	lambda integrase-like, N-terminal domain	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
G [auth A]	d1ouqa2	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
H [auth B]	d1ouqb1	All alpha proteins	SAM domain-like	lambda integrase-like, N-terminal domain	lambda integrase-like, N-terminal domain	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
H [auth B]	d1ouqb2	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
I [auth E]	d1ouqe1	All alpha proteins	SAM domain-like	lambda integrase-like, N-terminal domain	lambda integrase-like, N-terminal domain	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
I [auth E]	d1ouqe2	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
J [auth F]	d1ouqf1	All alpha proteins	SAM domain-like	lambda integrase-like, N-terminal domain	lambda integrase-like, N-terminal domain	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)
J [auth F]	d1ouqf2	Alpha and beta proteins (a+b)	DNA breaking-rejoining enzymes	DNA breaking-rejoining enzymes	Lambda integrase-like, catalytic core	Cre recombinase	(Punavirus P1 ) [TaxId: 10678 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
G [auth A]	SCOP2B Superfamily	lambda integrase clamp domain-like	8040147	3000550	SCOP2B (2022-06-29)
G [auth A]	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8040148	3001127	SCOP2B (2022-06-29)
H [auth B]	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8040148	3001127	SCOP2B (2022-06-29)
H [auth B]	SCOP2B Superfamily	lambda integrase clamp domain-like	8040147	3000550	SCOP2B (2022-06-29)
I [auth E]	SCOP2B Superfamily	lambda integrase clamp domain-like	8040147	3000550	SCOP2B (2022-06-29)
I [auth E]	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8040148	3001127	SCOP2B (2022-06-29)
J [auth F]	SCOP2B Superfamily	lambda integrase clamp domain-like	8040147	3000550	SCOP2B (2022-06-29)
J [auth F]	SCOP2B Superfamily	DNA breaking-rejoining enzymes	8040148	3001127	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
G [auth A]	INT_Cre_C	e1ouqA2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: INT_Cre_C	ECOD (1.6)
G [auth A]	Phage_integrase_N	e1ouqA1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N	ECOD (1.6)
G [auth A]	Phage_int_SAM_4	e1ouqA3	A: alpha arrays	X: lambda integrase-N-like	H: lambda integrase-N (From Topology)	T: lambda integrase-N	F: Phage_int_SAM_4	ECOD (1.6)
H [auth B]	INT_Cre_C	e1ouqB2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: INT_Cre_C	ECOD (1.6)
H [auth B]	Phage_integrase_N	e1ouqB1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N	ECOD (1.6)
H [auth B]	Phage_int_SAM_4	e1ouqB3	A: alpha arrays	X: lambda integrase-N-like	H: lambda integrase-N (From Topology)	T: lambda integrase-N	F: Phage_int_SAM_4	ECOD (1.6)
I [auth E]	INT_Cre_C	e1ouqE2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: INT_Cre_C	ECOD (1.6)
I [auth E]	Phage_integrase_N	e1ouqE1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N	ECOD (1.6)
I [auth E]	Phage_int_SAM_4	e1ouqE3	A: alpha arrays	X: lambda integrase-N-like	H: lambda integrase-N (From Topology)	T: lambda integrase-N	F: Phage_int_SAM_4	ECOD (1.6)
J [auth F]	INT_Cre_C	e1ouqF2	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: INT_Cre_C	ECOD (1.6)
J [auth F]	Phage_integrase_N	e1ouqF1	A: alpha arrays	X: HTH	H: HTH	T: DNA breaking-rejoining enzymes	F: Phage_integrase_N	ECOD (1.6)
J [auth F]	Phage_int_SAM_4	e1ouqF3	A: alpha arrays	X: lambda integrase-N-like	H: lambda integrase-N (From Topology)	T: lambda integrase-N	F: Phage_int_SAM_4	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
G [auth A]	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
G [auth A]	1.10.150.130	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
H [auth B]	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
H [auth B]	1.10.150.130	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
I [auth E]	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
I [auth E]	1.10.150.130	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)
J [auth F]	1.10.443.10	Mainly Alpha	Orthogonal Bundle	hpI Integrase	Chain A	CATH (4.3.0)
J [auth F]	1.10.150.130	Mainly Alpha	Orthogonal Bundle	DNA polymerase	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
G [auth A], H [auth B], I [auth E], J [auth F]	PF00589	Phage integrase family (Phage_integrase)	Phage integrase family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], D [auth G]	loxP DNA	-	-	-
B [auth X], E [auth Y]	loxP DNA	-	-	-
C [auth D], F [auth H]	loxP DNA	-	-	-
G [auth A], H [auth B], I [auth E], J [auth F]	Cre recombinase	DNA binding binding organic cyclic compound binding nucleic acid binding	nucleobase-containing compound metabolic process organic cyclic compound metabolic process organic substance metabolic process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process DNA integration nucleic acid metabolic process DNA recombination	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
G [auth A], H [auth B], I [auth E], J [auth F]	IPR011010	DNA breaking-rejoining enzyme, catalytic core	Homologous Superfamily
G [auth A], H [auth B], I [auth E], J [auth F]	IPR010998	Integrase/recombinase, N-terminal	Homologous Superfamily
G [auth A], H [auth B], I [auth E], J [auth F]	IPR044068	Core-binding (CB) domain	Domain
G [auth A], H [auth B], I [auth E], J [auth F]	IPR002104	Integrase, catalytic domain	Domain
G [auth A], H [auth B], I [auth E], J [auth F]	IPR013762	Integrase-like, catalytic domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.