1M4L
STRUCTURE OF NATIVE CARBOXYPEPTIDASE A AT 1.25 RESOLUTION
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d1m4la_ | Alpha and beta proteins (a/b) | Phosphorylase/hydrolase-like | Zn-dependent exopeptidases | Pancreatic carboxypeptidases | Carboxypeptidase A | (Bos taurus ) [TaxId: 9913 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Zn-dependent exopeptidases | 8044569 | 3000662 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.40.630.10 | Alpha Beta | 3-Layer(aba) Sandwich | Aminopeptidase | Zn peptidases | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00246 | Zinc carboxypeptidase (Peptidase_M14) | Zinc carboxypeptidase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036990 | Metallocarboxypeptidase-like, propeptide | Homologous Superfamily | |
IPR034248 | Carboxypeptidase A, carboxypeptidase domain | Domain | |
IPR003146 | Carboxypeptidase, activation peptide | Domain | |
IPR000834 | Peptidase M14, carboxypeptidase A | Domain |
Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage
Chains | Enzyme Name | Description | Catalytic Residues |
---|---|---|---|
carboxypeptidase A M-CSA #171 | A zinc dependent carboxypeptidase that catalyses the release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. | Defined by 5 residues: HIS:A-69GLU:A-72ARG:A-127HIS:A-196GLU:A-270 | EC: 3.4.17.1 (PDB Primary Data) |