Annotations: 1KCA

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1kcaa_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
B	d1kcab_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
C	d1kcac_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
D	d1kcad_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
E	d1kcae_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
F	d1kcaf_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
G	d1kcag_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)
H	d1kcah_	All beta proteins	LexA/Signal peptidase	LexA/Signal peptidase	LexA-related	lambda repressor C-terminal domain	(Lambdavirus lambda ) [TaxId: 10710 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	LexA/Signal peptidase-like	8058185	3000103	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Peptidase_S24	e1kcaA1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
B	Peptidase_S24	e1kcaB1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
C	Peptidase_S24	e1kcaC1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
D	Peptidase_S24	e1kcaD1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
E	Peptidase_S24	e1kcaE1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
F	Peptidase_S24	e1kcaF1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
G	Peptidase_S24	e1kcaG1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)
H	Peptidase_S24	e1kcaH1	A: beta barrels	X: SH3	H: LexA/Signal peptidase (From Topology)	T: LexA/Signal peptidase	F: Peptidase_S24	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
B	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
C	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
D	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
E	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
F	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
G	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)
H	2.10.109.10	Mainly Beta	Ribbon	Umud Fragment, subunit A	Umud Fragment, subunit A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00717	Peptidase S24-like (Peptidase_S24)	Peptidase S24-like	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	REPRESSOR PROTEIN CI	DNA binding sequence-specific DNA binding sequence-specific double-stranded DNA binding transcription cis-regulatory region binding binding double-stranded DNA binding organic cyclic compound binding core promoter sequence-specific DNA binding nucleic acid binding transcription regulatory region nucleic acid binding identical protein binding protein binding	latent virus replication viral process viral latency release from viral latency latency-replication decision regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process latent virus replication viral process viral latency release from viral latency latency-replication decision regulation of cellular process negative regulation of biological process negative regulation of cellular metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription regulation of RNA metabolic process organic substance biosynthetic process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process negative regulation of DNA-templated transcription regulation of biological process cellular metabolic process negative regulation of metabolic process primary metabolic process regulation of cellular metabolic process negative regulation of cellular biosynthetic process organic cyclic compound metabolic process regulation of gene expression biosynthetic process negative regulation of transcription by competitive promoter binding negative regulation of macromolecule biosynthetic process organic cyclic compound biosynthetic process metabolic process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process negative regulation of RNA metabolic process cellular biosynthetic process RNA metabolic process RNA biosynthetic process nucleic acid biosynthetic process organic substance metabolic process negative regulation of cellular process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process biological regulation regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of cellular biosynthetic process negative regulation of biosynthetic process cellular process maintenance of viral latency viral gene expression regulation of viral process regulation of viral transcription positive regulation of viral process positive regulation of biological process viral transcription positive regulation of viral transcription	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR015927	Peptidase S24/S26A/S26B/S26C	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001387	Cro/C1-type helix-turn-helix domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR039418	LexA-like	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036286	LexA/Signal peptidase-like superfamily	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR010982	Lambda repressor-like, DNA-binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the National Science Foundation (DBI-1832184), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM133198.